What are markers for bone cancer?

Tumour markers such as PSA, CEA, CA 19-9, AFP, CA 15-3 and bone marker levels were correlated with the presence or absence of bone scan-documented metastases. Results: Both of the bone markers examined were elevated in a high proportion of patients with confirmed metastases to bone.

How is osteosarcoma diagnosed?

How is osteosarcoma diagnosed? An x-ray is often the first diagnostic test that osteosarcoma patients receive, and an experienced radiologist may recognize immediately that bone cancer is the likely diagnosis.

What are potential immunohistochemical and immunohistochemical stains that could be used to differentiate osteosarcoma from other sarcomas?

Immunohistochemistry Staining Immunohistochemical stains performed on the sarcomas included vimentin (a marker for mesenchymal cells), smooth muscle actin (a marker for smooth muscle), myogenin (a specific marker for skeletal muscle), and F4/80 (a macrophage marker used to characterize histiocytic lesions).

What does bone scan show?

Bone scan can provide early detection of primary cancer and cancer that has spread to the bones from other parts of the body. Bone scan can detect osteomyelitis, an infection of the bone or bone marrow. Bone scan helps monitor the effects of treatment on bone abnormalities.

What is low grade osteosarcoma?

Low-grade central osteosarcoma is a rare variant of osteosarcoma that originates within the medullary cavity of bone and is often mistaken for fibrous dysplasia. At histologic examination, it appears as a Broders grade 1 or grade 2 lesion.

What are the types of osteosarcoma?

Types and subtypes of osteosarcoma

• Conventional central osteosarcoma, such as osteoblastic, chondroblastic, fibroblastic, and mixed types.
• Telangiectatic osteosarcoma.
• Intraosseous well-differentiated or low-grade central osteosarcoma.
• Small cell osteosarcoma.